Anti-osteoporosis agent-8
Product Specifications
Target
RANKL/RANK|||NF-?B|||p38 MAPK
Related Pathways
MAPK|||NF-?B
Bioactivity
Anti-osteoporosis agent-8 (Compound 4aa) is a RANKL inhibitor, capable of preventing RANKL-induced osteoclastogenesis and osteoclast differentiation, with an IC50 of 2.41 ?M. Furthermore, Anti-osteoporosis agent-8 has been shown to mitigate bone loss in an ovariectomized (OVX) mouse model.
Molecular Formula
C18H19F3N2O2Se
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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