HER2-IN-19
Product Specifications
Target
EGFR
Related Pathways
Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis
Bioactivity
HER2-IN-19 (Compound 10e) is a potent inhibitor of HER2 and EGFR, with IC50 values of 0.87 and 3.5 nM, respectively. It shows significant inhibitory activity against tumor cells, with IC50 values for NCI-N87, BT474, and BaF3-HER2YVMA being 1.63 nM, 15.17 nM, and 1.49 nM, respectively.
Molecular Formula
C30H29ClN6O2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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