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PD-1/PD-L1-IN-44

Product Specifications

Target

PD-1/PD-L1

Related Pathways

Apoptosis, Immunology/Inflammation, Cell Cycle/Checkpoint

Bioactivity

PD-1/PD-L1-IN-44 (Compound 22) selectively inhibits the PD-1/PD-L1 protein with an IC50 of 1.21 nM. In animal models, PD-1/PD-L1-IN-44 effectively suppressed tumor growth and increased CD8+ cell infiltration without exhibiting toxicity.

Molecular Formula

C34H30N2O6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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