PTPN2/1-IN-3
Product Specifications
Target
Phosphatase
Related Pathways
Metabolism
Bioactivity
PTPN2/1-IN-3 (compound 4) is an orally active PTPN2/N1 inhibitor, developed as an improved version of ABBV-CLS-484. It demonstrates antitumor activity, with an IC50 of 9.3 nM for inhibiting PTPN2, and exhibits oral bioavailability of 93% in mice.
Molecular Formula
C14H18FN3O4S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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