WS-384
Product Specifications
CAS Number
2247544-03-0
Target
DNA/RNA Synthesis, Caspase, E1/E2/E3 Enzyme, Apoptosis, Histone Demethylase
Related Pathways
Apoptosis, Proteases/Proteasome, Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Chromatin/Epigenetic, Ubiquitination
Bioactivity
WS-384 is an orally active dual inhibitor of LSD1 and DCN1-UBC12 protein-protein interactions, with IC50 values of 338.79 nM and 14.81 nM, respectively. It exhibits anticancer properties, causing cell cycle arrest, DNA damage, and inducing apoptosis (apoptosis) . WS-384 can be applied in research on non-small cell lung cancer (NSCLC) .
Smiles
Cl.BrC1=CC=C(C=C1)CSC=2N=C3N=C(C=C(SC4=NN=NN4CCN(C)C)N3N2)C
Molecular Formula
C18H21BrClN9S2
Molecular Weight
542.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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