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WS-384

Product Specifications

CAS Number

2247544-03-0

Target

DNA/RNA Synthesis, Caspase, E1/E2/E3 Enzyme, Apoptosis, Histone Demethylase

Related Pathways

Apoptosis, Proteases/Proteasome, Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Chromatin/Epigenetic, Ubiquitination

Bioactivity

WS-384 is an orally active dual inhibitor of LSD1 and DCN1-UBC12 protein-protein interactions, with IC50 values of 338.79 nM and 14.81 nM, respectively. It exhibits anticancer properties, causing cell cycle arrest, DNA damage, and inducing apoptosis (apoptosis) . WS-384 can be applied in research on non-small cell lung cancer (NSCLC) .

Smiles

Cl.BrC1=CC=C(C=C1)CSC=2N=C3N=C(C=C(SC4=NN=NN4CCN(C)C)N3N2)C

Molecular Formula

C18H21BrClN9S2

Molecular Weight

542.91

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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