AurkA allosteric-IN-1
Product Specifications
Target
Aurora Kinase
Related Pathways
Cell Cycle/Checkpoint|||Chromatin/Epigenetic
Bioactivity
AurkA allosteric-IN-1 (compound 6h) is an Aurora A (AurkA) inhibitor with an IC50 of 6.50 ?M, which inhibits both the catalytic and non-catalytic activities of Aurora A. Aurora A is involved in the regulation of bipolar mitotic spindle assembly and the fidelity of chromosome segregation during mitosis. AurkA allosteric-IN-1 interferes with Aurora A by binding to the Y-pocket, thereby preventing its interaction with the activator TPX2.
Molecular Formula
C20H16N2O3
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1452516-01 0.02 mg (E-Coli)
Recombinant Drosophila melanogaster N-alpha-acetyltransferase 30 (CG11412)
Ask
View Details MBS1452516-02 0.02 mg (Yeast)
Recombinant Drosophila melanogaster N-alpha-acetyltransferase 30 (CG11412)
Ask
View Details 
MBS1452516-03 0.1 mg (E-Coli)
Recombinant Drosophila melanogaster N-alpha-acetyltransferase 30 (CG11412)
Ask
View Details MBS1452516-04 0.1 mg (Yeast)
Recombinant Drosophila melanogaster N-alpha-acetyltransferase 30 (CG11412)
Ask
View Details MBS1452516-05 0.02 mg (Baculovirus)
Recombinant Drosophila melanogaster N-alpha-acetyltransferase 30 (CG11412)
Ask
View Details