LC-1-40
Product Specifications
Target
PROTACs, Apoptosis, DNA/RNA Synthesis
Related Pathways
Apoptosis, PROTAC, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Bioactivity
LC-1-40 is a PROTAC that selectively degrades NUDT1 (DC50=0.97 nM) . In mouse models, LC-1-40 selectively inhibits tumor growth induced by MYCN and induces nucleotide damage and apoptosis (cell death) in MYCN-associated tumors. It is applicable for cancer research.
Molecular Formula
C49H48N8O6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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