PROTAC GSK-3? Degrader-1
Product Specifications
Target
GSK-3|||PROTACs
Related Pathways
PI3K/Akt/mTOR signaling|||Stem Cells|||PROTAC
Bioactivity
PROTACGSK-3? Degrader-1 (compound 1) is a degrader targeting GSK-3? with an IC50 of 833 nM. This compound consists of SB-216763 (a GSK-3? inhibitor), a PEG linker, and CRBN (E3 ligase ligand) . It reduces neurotoxicity induced by A?25-35 peptide and CuSO4 and is applicable in Alzheimer's disease research.
Molecular Formula
C43H42Cl2N6O9
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1229217-01 0.02 mg (E-Coli)
Recombinant Salmonella paratyphi B UPF0231 protein yacL (yacL)
Ask
View Details MBS1229217-02 0.1 mg (E-Coli)
Recombinant Salmonella paratyphi B UPF0231 protein yacL (yacL)
Ask
View Details MBS1229217-03 0.02 mg (Yeast)
Recombinant Salmonella paratyphi B UPF0231 protein yacL (yacL)
Ask
View Details MBS1229217-04 0.1 mg (Yeast)
Recombinant Salmonella paratyphi B UPF0231 protein yacL (yacL)
Ask
View Details MBS1229217-05 0.02 mg (Baculovirus)
Recombinant Salmonella paratyphi B UPF0231 protein yacL (yacL)
Ask
View Details