Nav1.7-IN-13
Product Specifications
CAS Number
2776235-57-3
Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
Nav1.7-IN-13 (compound 3g) is a sodium channel inhibitor that notably suppresses Veratridine-induced neuronal activity. It inhibits the total Na+ current in DRG neurons in a concentration-dependent manner and delays the activation of Navs. Nav1.7-IN-13 significantly alleviates mechanical pain behavior in a rat model of nerve injury (SNI), exhibiting analgesic properties.
Smiles
C(OC)(=O)[C@@]1(CC=2C(O1)=CC=CC2)[C@@]3(O)C=4C(N(CC=C(C)C)C3=O)=CC(Br)=CC4
Molecular Formula
C23H22BrNO5
Molecular Weight
472.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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