MMP-9/10-IN-1

MMP-9/10-IN-1 (Compound 6b) is a potent dual inhibitor of MMP-9/10, with IC50 values of 0.076 μM for NSCLC cells and 0.139 μM for A549 cells. When combined with Sorafenib, it exhibits anti-invasive and anti-angiogenic properties.