B-Raf IN 17
Product Specifications
Target
Raf, FGFR, VEGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, MAPK
Bioactivity
B-Raf IN 17 (Compound 8e) is an effective, orally active type II multi-kinase inhibitor. It shows potent cellular inhibition against BRAFWT, VEGFR-2, and FGFR-1 in the A375 cell line, with IC50 values of 0.02, 0.18, and 1.65 μM, respectively. B-Raf IN 17 is applicable for cancer research.
Molecular Formula
C22H14BrN5O2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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