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B-Raf IN 17

Product Specifications

Target

Raf|||FGFR|||VEGFR

Related Pathways

Angiogenesis|||Tyrosine Kinase/Adaptors|||MAPK

Bioactivity

B-Raf IN 17 (Compound 8e) is an effective, orally active type II multi-kinase inhibitor. It shows potent cellular inhibition against BRAFWT, VEGFR-2, and FGFR-1 in the A375 cell line, with IC50 values of 0.02, 0.18, and 1.65 ?M, respectively. B-Raf IN 17 is applicable for cancer research.

Molecular Formula

C22H14BrN5O2

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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