LM-021
Product Specifications
CAS Number
1022282-98-9
Target
Interleukin|||Reactive Oxygen Species|||Dehydrogenase|||Caspase
Related Pathways
Metabolism|||Immunology/Inflammation|||Proteases/Proteasome|||Apoptosis|||NF-?B
Bioactivity
LM-021, a coumarin-chalcone derivative, exhibits properties such as anti-aggregation, antioxidant, neuroprotective, and anti-inflammatory effects. It inhibits the production of nitric oxide (NO), IL-1?, IL-6, and TNF-?, as well as the expression of CD68 and MHCII. Additionally, LM-021 reduces caspase 1 activity, lactate dehydrogenase release, and ROS level elevation. It is used in neurological research.
Smiles
OC=1C=2C(OC(=O)C1C(/C=C/C3=CC=C(N(C)C)C=C3)=O)=CC=CC2
Molecular Formula
C20H17NO4
Molecular Weight
335.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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