PROTAC HPK1 Degrader-1
Product Specifications
CAS Number
3034182-97-0
Target
PROTACs, MAPK
Related Pathways
PROTAC, MAPK
Bioactivity
PROTACHPK1 Degrader-1 (Compound B1) is a potent HPK1 degrader with a DC50 value of 1.8 nM. It effectively inhibits the phosphorylation of the SLP76 protein, with an IC50 of 496.1 nM. As a genuine HPK1-PROTAC degrader, PROTACHPK1 Degrader-1 offers a valuable tool for further investigation into HPK1 in TCR signaling pathways.
Smiles
O=C1C=2C=CC=C(NCCOCCC(=O)N3CCN(C=4C=CC(=CC4)C5=CN=C6NC=C(C=7C=CC(OC)=C(OC)C7)C6=C5)CC3)C2C(=O)N1C8C(=O)NC(=O)CC8
Molecular Formula
C43H43N7O8
Molecular Weight
785.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LC420315 20 µg
TMEM176B (NM_001101314) Human Over-expression Lysate
Sign In for Pricing
View Details 
![CD1 (CD1A) Mouse Monoclonal Antibody [Clone ID: O10]](https://cdn.genprice.uk/products/937/68dd189e061270361e8fd586/imageurl/am33361pu-t.webp)
AM33361PU-T 20 µg
CD1 (CD1A) Mouse Monoclonal Antibody [Clone ID: O10]
Sign In for Pricing
View Details ![RNase L Recombinant Rabbit Monoclonal Antibody [JE36-11]](https://cdn.genprice.uk/products/992/68dd1c8e061270361ea822d3/imageurl/ha722221.webp)
HA722221 100 µL
RNase L Recombinant Rabbit Monoclonal Antibody [JE36-11]
Sign In for Pricing
View Details