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CYP17A1/HDAC6-IN-1

Product Specifications

CAS Number

3047489-22-2

Target

Cytochromes P450|||HDAC

Related Pathways

Metabolism|||DNA Damage/DNA Repair|||Chromatin/Epigenetic

Bioactivity

CYP17A1/HDAC6-IN-1 (compound 12) is a potent inhibitor of CYP17A1 and HDAC6, with IC50 values of 0.284 ?M and 0.6015 ?M, respectively. It exhibits antitumor activity.

Smiles

C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](OC(CCCCCC(NO)=O)=O)CC4)(CC1)[H])[H])(CC=C2C=5C=CC=NC5)[H]

Molecular Formula

C31H42N2O4

Molecular Weight

506.68

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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