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NB512

Product Specifications

Target

Epigenetic Reader Domain, HDAC

Related Pathways

DNA Damage/DNA Repair, Chromatin/Epigenetic

Bioactivity

NB512 (compound 39a) is a dual inhibitor targeting both BET and HDAC, exhibiting high affinity for the BRD4 bromodomain and HDAC1/2, with EC50 values ranging from 100 to 400 nM. It demonstrates antiproliferative activity in cancer cell lines PaTu8988T and NMC.

Molecular Formula

C26H21N5O2

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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