Cbl-b-IN-16
Product Specifications
Target
E1/E2/E3 Enzyme
Related Pathways
Ubiquitination
Bioactivity
Cbl-b-IN-16 (compound 31) is an orally active inhibitor of the RING E3 ligase Cbl-b, with an IC50 of 30 nM. It enhances IL-2 production in human T cells with an EC50 of 230 nM and exhibits antitumor activity.
Molecular Formula
C26H27F3N6O
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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