PRMT5-IN-33

Product Specifications

Target

Apoptosis|||Histone Methyltransferase

Related Pathways

Apoptosis|||Chromatin/Epigenetic

Bioactivity

PRMT5-IN-33 (compound A8) is a selective inhibitor of PRMT5 that competes with SAM, exhibiting an IC50 of 10.9 nM. It induces apoptosis and inhibits the proliferation of Z-138 and MOLM-13 cells, demonstrating antitumor activity.

Molecular Formula

C25H24BrN5O3S

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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