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P-gp inhibitor 20

Product Specifications

Target

P-gp

Related Pathways

Neuroscience|||Membrane transporter/Ion channel

Bioactivity

P-gp inhibitor 20 (Compound H27) is a P-glycoprotein (P-gp) inhibitor characterized by low cytotoxicity. It reverses multidrug resistance (MDR) in MCF-7/ADR cells by inhibiting the efflux function of P-gp in a dose-dependent manner without affecting P-gp expression, with an IC50 value of 46.6 nM. P-gp inhibitor 20 is suitable for cancer research.

Molecular Formula

C30H28N4O3Se

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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