WK369
Product Specifications
Target
Apoptosis, Bcl-6
Related Pathways
Apoptosis, Immunology/Inflammation
Bioactivity
WK369 is an innovative small molecule inhibitor of BCL6, demonstrating remarkable bioactivity against ovarian cancer by inducing cell cycle arrest and triggering apoptosis. It binds directly to the BCL6-BTB domain, obstructing the interaction between BCL6 and SMRT, which results in the reactivation of p53, ATR, and CDKN1A.
Molecular Formula
C19H20FN5O2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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