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HDAC6-IN-31

Product Specifications

Target

HDAC

Related Pathways

Chromatin/Epigenetic, DNA Damage/DNA Repair

Bioactivity

HDAC6-IN-31 (compound 8m) is a selective HDAC6 inhibitor with an IC50 of 0.026 μM. It significantly suppresses the production and release of pro-inflammatory cytokines. HDAC6 plays a crucial role in inhibiting inflammasome activation and holds potential for treating NLRP3 inflammasome-driven inflammatory diseases. Additionally, HDAC6-IN-31 inhibits the migration of glioblastoma cells.

Molecular Formula

C15H13FN4O2

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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