AK-HW-90
Product Specifications
Target
Bcr-Abl
Related Pathways
Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Angiogenesis
Bioactivity
AK-HW-90 (compound 2B) is a potent pan-Bcr-Abl inhibitor that shows significant inhibitory activity against Imatinib-resistant mutants. It inhibits the resistant Bcr-AblT315I mutant with an IC50 of 0.65 nM. AK-HW-90 offers potential anti-cancer properties and can be utilized in chronic myeloid leukemia (CML) research.
Molecular Formula
C27H29N5O2S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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