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AK-HW-90

Product Specifications

Target

Bcr-Abl

Related Pathways

Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Angiogenesis

Bioactivity

AK-HW-90 (compound 2B) is a potent pan-Bcr-Abl inhibitor that shows significant inhibitory activity against Imatinib-resistant mutants. It inhibits the resistant Bcr-AblT315I mutant with an IC50 of 0.65 nM. AK-HW-90 offers potential anti-cancer properties and can be utilized in chronic myeloid leukemia (CML) research.

Molecular Formula

C27H29N5O2S

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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