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JAK1-IN-14

Product Specifications

Target

JAK

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Stem Cells, JAK/STAT signaling

Bioactivity

JAK1-IN-14 (Compound12a) is a potent and selective inhibitor of JAK1, effectively inhibiting JAK1 and JAK2 with IC50 values of 12.6 nM and 135 nM, respectively. It reduces liver fibrosis levels and is applicable for research related to liver fibrosis and inflammatory diseases.

Molecular Formula

C20H30N6O

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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