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WD6305

Product Specifications

Target

PROTACs, Apoptosis

Related Pathways

PROTAC, Apoptosis

Bioactivity

WD6305 is an effective and selective METTL3-METTL14 PROTAC degrader, with DC50 values of 140 nM and 194 nM for METTL3 and METTL14, respectively. It inhibits m6A modification and the proliferation of acute myeloid leukemia cells while inducing apoptosis. WD6305 also exhibits antitumor activity.

Molecular Formula

C61H75F2N11O5S

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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