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Menin-MLL inhibitor-25

Product Specifications

Target

Epigenetic Reader Domain|||Apoptosis

Related Pathways

Apoptosis|||Chromatin/Epigenetic

Bioactivity

Menin-MLL inhibitor-25 (compound A6) is a potent inhibitor of the Menin-MLL interaction, with an IC50 of 0.38 µM. It exhibits antiproliferative activity, induces apoptosis and G0/G1 cell cycle arrest, and can reverse differentiation arrest.

Molecular Formula

C28H28FN7

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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