What is the catalog number for CSC-6?

The catalog number for CSC-6 is T208801.

What sizes are available for CSC-6?

CSC-6 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does CSC-6 come in?

CSC-6 is available in 2 different pack sizes.

CSC-6 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CSC-6?

CSC-6 is manufactured by Molfinity.

What is the estimated delivery time for CSC-6?

Estimated delivery time for CSC-6 is approximately 10 business day(s), depending on your location.

CSC-6

Product Specifications

Target

NOD-like Receptor (NLR)

Related Pathways

Immunology/Inflammation

Bioactivity

CSC-6 is an inhibitor of NLRP3. It significantly reduces the secretion of IL-1β in PMATHP-1 cells, with an IC50 of 2.3 μM. CSC-6 specifically binds to NLRP3 and prevents its activation by obstructing ASC oligomerization during the NLRP3 assembly process. It effectively alleviates symptoms of sepsis and gout mediated by excessive NLRP3 activation in mouse models.