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PDEδ autophagic degrader 1

Product Specifications

Target

Autophagy, PDE, ATTECs

Related Pathways

Autophagy, Metabolism, PROTAC

Bioactivity

PDEδ autophagic degrader 1 (compound 12c) is an autophagosome-tethering compound (ATTEC) and a potent autophagic degrader of PDEδ. This compound effectively reduces PDEδ protein levels through lysosome-mediated autophagy without affecting PDEδ mRNA expression. Additionally, PDEδ autophagic degrader 1 inhibits the growth of KRAS mutant pancreatic cancer cells.

Molecular Formula

C41H42Br2IN7O5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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