PDEδ autophagic degrader 1
Product Specifications
Target
Autophagy, PDE, ATTECs
Related Pathways
Autophagy, Metabolism, PROTAC
Bioactivity
PDEδ autophagic degrader 1 (compound 12c) is an autophagosome-tethering compound (ATTEC) and a potent autophagic degrader of PDEδ. This compound effectively reduces PDEδ protein levels through lysosome-mediated autophagy without affecting PDEδ mRNA expression. Additionally, PDEδ autophagic degrader 1 inhibits the growth of KRAS mutant pancreatic cancer cells.
Molecular Formula
C41H42Br2IN7O5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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