BET-IN-21
Product Specifications
CAS Number
3014815-06-3
Target
Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic
Bioactivity
BET-IN-21 (compound 16) is a BET (Bromo and Extra-Terminal domain) inhibitor capable of penetrating the blood-brain barrier, with a Ki value of 230 nM. It suppresses microglial activation and demonstrates therapeutic effects in mice with experimental autoimmune encephalomyelitis.
Smiles
N=1C=C(C=C(C1)C=2C(=NN(C2C)CC3CC3)C)C4=CC=NC=5N=CNC54
Molecular Formula
C20H20N6
Molecular Weight
344.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
035991-ML550 100 µL
GDPD3, NT (GDPD3, Glycerophosphodiester phosphodiesterase domain-containing protein 3) (MaxLight 550) discontinued
Sign In for Pricing
View Details 
TRV-0024090-01 200 µL
FITC-Linked Polyclonal Antibody to Catalase (CAT)
Sign In for Pricing
View Details TRV-0024090-02 1 mL
FITC-Linked Polyclonal Antibody to Catalase (CAT)
Sign In for Pricing
View Details 
130151-APC 100 µL
NARS (Asparagine-tRNA Ligase, Cytoplasmic, Asparaginyl-tRNA Synthetase, AsnRS) (APC)
Sign In for Pricing
View Details