HDAC6-IN-28
Product Specifications
Target
Apoptosis, HDAC
Related Pathways
DNA Damage/DNA Repair, Apoptosis, Chromatin/Epigenetic
Bioactivity
HDAC6-IN-28 (compound 10C) is a potent inhibitor of HDAC6 with an IC50 of 261 nM. It significantly induces apoptosis in B16-F10 cells and causes S phase arrest. Additionally, HDAC6-IN-28 effectively increases the expression of acetylated-α-tubulin both in vitro and in vivo.
Molecular Formula
C23H16FN3O2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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