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Thalidomide-4-NH-PEG1-COOH TFA

Product Specifications

CAS Number

2140807-20-9

Target

E3 Ligase Ligand-Linker Conjugate

Related Pathways

PROTAC

Bioactivity

Thalidomide-4-NH-PEG1-COOH TFA is a conjugate of an E3 ligase ligand and linker, composed of Thalidomide and NH-PEG3-NH-Boc. It serves as a Cereblon? ligand, facilitating the recruitment of CRBN? protein. This compound is a crucial intermediate in the synthesis of PROTAC molecules designed based on CRBN.

Smiles

O=C(O)CCOCCNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3.O=C(O)C(F)(F)F

Molecular Formula

C20H20F3N3O9

Molecular Weight

503.38

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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