HTRA1-IN-1
Product Specifications
CAS Number
3052552-04-9
Target
Serine Protease
Related Pathways
Proteases/Proteasome
Bioactivity
HTRA1-IN-1 (Compound 17) is a selective inhibitor of the serine protease high temperature requirement A serine peptidase 1 (HTRA1), with an IC50 of 13 nM. It shows potential for improving conditions related to HTRA1, such as age-related macular degeneration (AMD), osteoarthritis, and rheumatoid arthritis.
Smiles
[C@H](CC1=CC(Cl)=CC=C1)(C(N[C@H](C(N[C@H](B(O)O)C2CCC2)=O)CC(C)C)=O)NC(C(CC3=CC=CC=C3)(C)C)=O
Molecular Formula
C31H43BClN3O5
Molecular Weight
583.95
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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