HR488B
Product Specifications
Target
Apoptosis, Reactive Oxygen Species, HDAC
Related Pathways
Immunology/Inflammation, Apoptosis, Chromatin/Epigenetic, NF-κB, Metabolism, DNA Damage/DNA Repair
Bioactivity
HR488B is a potent inhibitor of HDAC1. It specifically hinders the growth of CRC cells by inducing cell cycle arrest at the G0/G1 phase and promoting apoptosis. Furthermore, HR488B leads to mitochondrial dysfunction, the production of reactive oxygen species (ROS), and the accumulation of DNA damage.
Molecular Formula
C24H26ClN3O4S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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