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LasB-IN-1

Product Specifications

Target

Antibacterial, NF-κB, p38 MAPK, Serine Protease

Related Pathways

MAPK, Microbiology/Virology, Proteases/Proteasome, NF-κB

Bioactivity

LasB-IN-1 (compound 5f) is an efficient and orally active inhibitor of LasB (IC50 = 8.7 μM) . It effectively inhibits elastase production and biofilm formation in Pseudomonas aeruginosa, while also attenuating inflammatory responses by downregulating MAPK and NF-κB pathways. LasB-IN-1 holds potential as a candidate agent against drug-resistant infections.

Molecular Formula

C20H22F3NO2

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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