Tubulin/PARP-IN-1
Product Specifications
Target
PARP|||Microtubule Associated
Related Pathways
Cytoskeletal Signaling|||DNA Damage/DNA Repair|||Chromatin/Epigenetic
Bioactivity
Tubulin/PARP-IN-1 (compound 14) is a dual PARP-tubulin inhibitor with anti-endometrial cancer activity. It exhibits inhibitory concentration (IC50) values of 74 nM for PARP1, 109 nM for PARP2, and 1.4 ?M for microtubules/tubulin. Tubulin/PARP-IN-1 induces apoptosis and autophagy, causing cell cycle arrest at the G2/M phase.
Molecular Formula
C19H13FO3
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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