Androgen receptor-IN-6
Product Specifications
CAS Number
3016437-05-8
Target
Androgen Receptor
Related Pathways
Endocrinology/Hormones
Bioactivity
Androgen receptor-IN-6 (compound 16) is an orally active and potent inhibitor of the androgen receptor (IC50=0.12 μMin vitro), targeting its disordered N-terminal domain (NTD) . It demonstrates good permeability in Caco2 cell membranes and exhibits an oral bioavailability (F/%) of 16% in male CD-1 mice.
Smiles
O=C(N)C1=CC=C(SC)C(=C1)C2=CC=C3C(C=NN3C)=C2
Molecular Formula
C16H15N3OS
Molecular Weight
297.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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