PqsR-IN-3
Product Specifications
CAS Number
3033007-79-0
Target
Antibacterial
Related Pathways
Microbiology/Virology
Bioactivity
PqsR-IN-3 (compound 16e) is a selective inhibitor of the pqs system (IC50=3.7 μM) and its associated virulence factor pyocyanin (IC50=2.7 μM) . This compound inhibits the synthesis of bacterial biofilms and is significantly cytotoxic to Pseudomonas aeruginosa. Additionally, PqsR-IN-3 exhibits synergistic effects with various antibiotics, such as Ciprofloxacin and Tobramycin.
Smiles
O=C1C=C(N(C(=C1O)CNCC=2N=NN(C2)C3=CC=C(OC=4C=CC=CC4)C=C3)C)C
Molecular Formula
C23H23N5O3
Molecular Weight
417.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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