VEGFR-2/AURKA-IN-1
Product Specifications
Target
Aurora Kinase|||VEGFR
Related Pathways
Angiogenesis|||Tyrosine Kinase/Adaptors|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic
Bioactivity
VEGFR-2/AURKA-IN-1 (compound 5e) is a thiazolidin-4-one derivative with antitumor activity against glioma (IC50: 6.43 ?M in LN229 cells) . This compound exhibits affinity for AURKA and VEGFR-2, acting as a potential ligand. VEGFR-2/AURKA-IN-1 induces DNA strand breaks, showcasing cytotoxicity and anticancer potential.
Molecular Formula
C20H15ClF6N2O4S
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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