Thalidomide-O-amido-C11-COOH
Product Specifications
CAS Number
2473270-96-9
Target
E3 Ligase Ligand-Linker Conjugate
Related Pathways
PROTAC
Bioactivity
Thalidomide-O-amido-C11-COOH (Compound IMiD acid 1) is a compound that acts as an E3 ligase ligand and linker for the CRBN (Cereblon) conjugate. This compound is useful in synthesizing PROTACs targeting the degradation of DOT1L.
Smiles
O=C(O)CCCCCCCCCCCNC(=O)COC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
Molecular Formula
C27H35N3O8
Molecular Weight
529.58
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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