What is the catalog number for EGFR/c-Met-IN-1?

The catalog number for EGFR/c-Met-IN-1 is T208266.

What sizes are available for EGFR/c-Met-IN-1?

EGFR/c-Met-IN-1 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does EGFR/c-Met-IN-1 come in?

EGFR/c-Met-IN-1 is available in 2 different pack sizes.

Is EGFR/c-Met-IN-1 in stock?

EGFR/c-Met-IN-1 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EGFR/c-Met-IN-1?

EGFR/c-Met-IN-1 is manufactured by Molfinity.

What is the estimated delivery time for EGFR/c-Met-IN-1?

Estimated delivery time for EGFR/c-Met-IN-1 is approximately 10 business day(s), depending on your location.

EGFR/c-Met-IN-1

Product Specifications

CAS Number

3020728-68-8

Target

C-Met/HGFR, EGFR

Related Pathways

Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis

Bioactivity

EGFR/c-Met-IN-1 (compound TS-41) is a dual inhibitor targeting EGFR and c-Met, with IC50 values of 68.1 nM for EGFRL858R and 0.26 nM for c-Met. EGFR/c-Met-IN-1 induces apoptosis and cell cycle arrest in A549-P cells, and reduces phosphorylation of EGFR, c-Met, and downstream AKT. This compound effectively inhibits tumor growth both in vitro and in vivo.