PB94
Product Specifications
CAS Number
3032970-74-1
Target
HDAC
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair
Bioactivity
PB94 is a selective inhibitor of HDAC11 with an IC50 value of 108 nM. This compound can be radiolabeled as [11C]-PB94 for use in positron emission tomography (PET) to study brain uptake and metabolic characteristics in living animals. Furthermore, PB94 has been shown to alleviate neuropathic pain in mice and is applicable for research into neurological indications.
Smiles
O=C(NCC12CC3CC(CC(C3)C1)C2)C=4C=CC5=C(C=CN5CC6=CC=C(C(=O)NO)C(OC)=C6)C4
Molecular Formula
C29H33N3O4
Molecular Weight
487.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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