Tapcin
Product Specifications
Target
Topoisomerase
Related Pathways
DNA Damage/DNA Repair
Bioactivity
Tapcin is a dual inhibitor of topoisomerase I and II, with IC50 values of 203 nM and 71 nM, respectively. It effectively inhibits the proliferation of cancer cells such as A-375, HeLa, Huh7.5, U2-OS, A549, Caco-2, and HT29, with IC50 values of 441, 1.04, 40.5, 0.002, 0.006, 0.287, and 0.842 nM, respectively. Additionally, Tapcin demonstrates antitumor activity in HT29 xenograft models.
Molecular Formula
C64H73N11O13S3
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1207849-01 0.02 mg (E-Coli)
Recombinant Burkholderia mallei Bis (5'-nucleosyl) -tetraphosphatase, symmetrical
Ask
View Details 
MBS1207849-02 0.02 mg (Yeast)
Recombinant Burkholderia mallei Bis (5'-nucleosyl) -tetraphosphatase, symmetrical
Ask
View Details 
MBS1207849-03 0.1 mg (E-Coli)
Recombinant Burkholderia mallei Bis (5'-nucleosyl) -tetraphosphatase, symmetrical
Ask
View Details