AGB1
Product Specifications
Target
Others
Related Pathways
Others
Bioactivity
AGB1 is a highly selective and potent B&H-PROTAC degrader. It degrades Ab:Brd4BD2 L387A and Ab:BromoTag-Brd2 with pDC50 values of 7.8 and 7.9, respectively. AGB1 has an affinity for VHL with a Kd of 125 nM. In mice, AGB1 exhibits favorable pharmacokinetic properties [DC50, 6 h approximately 13 nM].
Molecular Formula
C51H63ClN8O9S2
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/372420022380789813/T208182
Available Sizes
Curated Selection
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