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AGB1

Product Specifications

Target

Others

Related Pathways

Others

Bioactivity

AGB1 is a highly selective and potent B&H-PROTAC degrader. It degrades Ab:Brd4BD2 L387A and Ab:BromoTag-Brd2 with pDC50 values of 7.8 and 7.9, respectively. AGB1 has an affinity for VHL with a Kd of 125 nM. In mice, AGB1 exhibits favorable pharmacokinetic properties [DC50, 6 h approximately 13 nM].

Molecular Formula

C51H63ClN8O9S2

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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