EN219-alkyne
Product Specifications
Target
Others
Related Pathways
Others
Bioactivity
EN219-alkyne is an alkyne-functionalized EN219 probe. EN219 is a synthetic covalent ligand with moderate specificity for the N-terminal cysteine (C8) of RNF114, exhibiting an IC50 of 470 nM. It inhibits RNF114-mediated autoubiquitination and p21 ubiquitination. EN219-alkyne acts as a click chemistry reagent, containing an alkyne group that can undergo a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing azide groups.
Molecular Formula
C22H19BrClN3O3
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/372420022347235340/T207869
Available Sizes
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