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TEAD1/3/4-IN-1

Product Specifications

CAS Number

2762619-63-4

Target

YAP

Related Pathways

Stem Cells

Purity

0.9925

Bioactivity

TEAD1/3/4-IN-1 (compound 1) is an inhibitor of TEAD1/3/4 that suppresses YAP/TAZ-TEAD interactions. It exhibits antitumour activity against NF2-deficient NCI-H226 cells and may be employed in studies of cancer and diseases mediated by Hippo pathway abnormalities.

Smiles

O=C(C(F)=C)N1CC(N2C(=O)N(C3=CC=C(C=C3)C(F)(F)F)C4=NC=CN=C42)C1

Molecular Formula

C18H13F4N5O2

Molecular Weight

407.32

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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