Tryptophan-cholic acid
Product Specifications
CAS Number
1630745-39-9
Target
GPCR, Endogenous Metabolite
Related Pathways
GPCR/G Protein, Endocrinology/Hormones, Metabolism
Purity
1
Bioactivity
Tryptophan-cholic acid (Trp-CA) is a microbial amino acid-binding bile acid (MABA), serving as an endogenous ligand and agonist for MRGPRE (Mas-related GPCR family member E), thereby inducing GLP-1 secretion. Tryptophan-cholic acid improves glucose tolerance in diabetic mice and may be utilised for studies on type 2 diabetes.
Smiles
O[C@H]1[C@]2([C@]3([C@@](C)([C@@]([C@@H](CCC(N[C@@H](CC=4C=5C(NC4)=CC=CC5)C(O)=O)=O)C)(CC3)[H])[C@@H](O)C[C@@]2([C@]6(C)[C@](C1)(C[C@H](O)CC6)[H])[H])[H])[H]
Molecular Formula
C35H50N2O6
Molecular Weight
594.78
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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