EZH2/HSP90-IN-29
Product Specifications
CAS Number
3033571-35-3
Target
Others
Related Pathways
Others
Bioactivity
EZH2/HSP90-IN-29 is a potent dual inhibitor of EZH2 and HSP90, with IC50 values of 6.29 nM and 60.1 nM, respectively. It induces cell cycle arrest at the M phase, promotes the expression of genes related to apoptosis/necrosis, and inhibits reactive oxygen species (ROS) catabolism. This compound can cross the blood-brain barrier, making it a promising and easily manageable candidate for glioblastoma (GBM) research.
Smiles
O=C(NCC=1C(=O)NC(=CC1C)C)C=2C=C(C=C(C2C)N(CC)C3CCOCC3)C=4C=CC=C(C4)N(C(=O)C=5C=C(C(O)=CC5O)C(C)C)C
Molecular Formula
C40H48N4O6
Molecular Weight
680.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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